Publications & Patents

Explore Theta Tech AI’s extensive body of peer-reviewed publications and patents, highlighting our team's deep expertise in healthcare-focused artificial intelligence. Our contributions span advanced algorithm design, machine learning methodologies, and real-world clinical AI applications, demonstrating thought leadership and tangible innovation in the healthcare industry.
Our Publications

Check (Out) Our Work

Explore our collection of 35+ Peer-Reviewed Publications and Patents.
Theses & Dissertations
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Improved Active Shape Models for Segmentation of the Prostate on MR Imagery
Toth, R. “Improved Active Shape Models for Segmentation of the Prostate on MR Imagery,” M.S. Thesis, Rutgers University, 2010.
Publications
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Evaluation of prostate segmentation algorithms for MRI: The PROMISE12 challenge
Litjens, G., Toth, R., van de Ven, W., Hoeks, C., Kerkstra, S., van Ginneken, B., Vincent, G., Guillard, G., Birbeck, N., Zhang, J., Strand, R., Malmberg, F., Ou, Y., Davatzikos, C., Kirschner, M., Jung, F., Yuan, J., Qiu, W., Gao, Q., Edwards, P.E., Maan, B., van der Heijden, F., Ghose, S., Mitra, J., Dowling, J., Barratt, D., Huisman, H., Madabhushi, A. “Evaluation of prostate segmentation algorithms for MRI: The PROMISE12 challenge.” Medical Image Analysis 25:18(2), Dec 2013 pp. 359-373. doi: 10.1016/j.media.2013.12.002
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HistostitcherTM: An informatics software platform for reconstructing whole-mount prostate histology using the extensible imaging platform framework
Toth, R.J., Shih, N., Tomaszewski, J.E., Feldman, M.D., Kutter, O., Yu, D.N., Paulus, J.C., Paladini, G., Madabhushi, A., “HistostitcherTM: An informatics software platform for reconstructing whole-mount prostate histology using the extensible imaging platform framework.” Journal of Pathology Informatics 5(8), Mar 2014. doi: 10.4103/2153-3539.129441
Publications
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A Domain Constrained Deformable (DoCD) Model for Co-registration of Pre- and Post-Radiated Prostate MRI
Toth, R., Traughber, B., Ellis, R., Kurhanewicz, J., Madabhushi, A., “A Domain Constrained Deformable (DoCD) Model for Co-registration of Pre- and Post-Radiated Prostate MRI.” Neurocomputing 144(20) Nov 2014. pp. 3-12 doi: 10.1016/j.neucom.2014.01.058
Theses & Dissertations
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Evaluating Treatment Related Changes for Prostate Cancer via Image Analysis Tools and Magnetic Resonance Imaging
Toth, R. “Evaluating Treatment Related Changes for Prostate Cancer via Image Analysis Tools and Magnetic Resonance Imaging”, Ph.D. Dissertation, Rutgers University, 2014.
Patents
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Computer Assisted Diagnosis (CAD) of Cancer Using Multi-Functional in vivo Magnetic Resonance Spectroscopy (MRS) and Imaging (MRI)
“Computer Assisted Diagnosis (CAD) of Cancer Using Multi-Functional in vivo Magnetic Resonance Spectroscopy (MRS) and Imaging (MRI)” by Anant Madabhushi, Satish Viswanath, Pallavi Tiwari, Robert Toth, Mark Rosen, John Tomaszeweski, Michael Feldman, PCT/US08/81656, Oct. 2008.
Patents
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Image Similarity-Based Finite Element Model Registration
“Image Similarity-Based Finite Element Model Registration” by Robert Toth, Anant Madabhushi, United States US 14/225,850, Mar, 2014.
Publications
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Simultaneous Segmentation of Prostatic Zones Using Active Appearance Models with Multiple Coupled Levelsets
Toth, R., Ribault, J., Gentile, J.C., Sperling, D., Madabhushi, A. “Simultaneous Segmentation of Prostatic Zones Using Active Appearance Models with Multiple Coupled Levelsets,” CVIU Special Issue on Shape Modeling 117(9), Sep 2013. pp. 1051-1060. doi: 10.1016/j.cviu.2012.11.013
Publications
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Automated Computer-Derived Prostate Volumes from MRI Data: Comparison to Radiologist-Derived MRI Volumes and Pathology Specimen Volumes
Bulman, J.C., Toth, R., Patel, A.D., Bloch, N.B., MacMahon C.J., Ngo L., Madabhushi, A., Rofsky, N.M., "Automated Computer-Derived Prostate Volumes from MRI Data: Comparison to Radiologist-Derived MRI Volumes and Pathology Specimen Volumes," Radiology 262 (1), Jan 2012. pp. 144-151. doi: 10.1148/radiol.11110266
Publications
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Multi-Feature Landmark-Free Active Appearance Models: Application to Prostate MRI Segmentation
Toth, R., Madabhushi, A., “Multi-Feature Landmark-Free Active Appearance Models: Application to Prostate MRI Segmentation,” IEEE TMI 31(8), pp. 1638-1650. Jun 2012. doi: 10.1109/TMI.2012.2201498
Publications
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A Magnetic Resonance Spectroscopy Driven Initialization Scheme for Active Shape Model Based Prostate Segmentation
Toth, R., Tiwari, P., Rosen, M., Reed, G., Kurhanewicz, J., Kalyanpur, A., Pungavkar, S., Madabhushi, A. “A Magnetic Resonance Spectroscopy Driven Initialization Scheme for Active Shape Model Based Prostate Segmentation.” Medical Image Analysis 15 (2), Apr 2011. pp. 214-225. doi: 10.1016/j.media.2010.09.002
Publications
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Accurate Prostate Volume Estimation Using Active Shape Models on T2-Weighted MRI
Toth, R., Bloch, N., Genega, E., Rofsky, N., Lenkinski, R., Rosen, M., Madabhushi, A. “Accurate Prostate Volume Estimation Using Active Shape Models on T2-Weighted MRI.” Academic Radiology 18 (2), Jun 2011, pp. 745-754. doi: 10.1016/j.acra.2011.01.016
Publications
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Central Gland and Peripheral Zone Prostate Tumors have Significantly Different Quantitative Imaging Signatures on 3 Tesla Endorectal, In Vivo T2-Weighted Magnetic Resonance Imagery
Viswanath, S, Bloch, B.N., Chappelow, J., Toth, R., Genega, E., Lenkinski, R., Rofsky, N., Madabhushi, A., “Central Gland and Peripheral Zone Prostate Tumors have Significantly Different Quantitative Imaging Signatures on 3 Tesla Endorectal, In Vivo T2-Weighted Magnetic Resonance Imagery”, Journal of Magnetic Resonance Imaging 36(1), 2012. pp. 213-224 doi: 10.1002/jmri.23618
Publications
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Concurrent segmentation of the prostate on MRI and CT via linked statistical shape models for radiotherapy planning
Chowdhury, N., Toth, R., Chappelow, J., Kim, S., Motwani, S., Punekar, S., Lin, H., Both, S., Vapiwala, N., Hahn, S., Madabushi, An. “Concurrent segmentation of the prostate on MRI and CT via linked statistical shape models for radiotherapy planning.” Medical Physics 39(4), Apr 2012, pp. 2214-2228. doi: 10.1118/1.3696376 (Editor’s Pick)
Conference Publication
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WERITAS: Weighted Ensemble of Regional Image Textures for ASM Segmentation
Toth, R., Doyle, S., Rosen, M., Pungavkar, S., Kalyanpur, A., Madabhushi, A., “WERITAS: Weighted Ensemble of Regional Image Textures for ASM Segmentation,” SPIE Medical Imaging 7258, pp. 725905-725905-11, 2009. doi: 10.1117/12.812473 (Best Paper Award)
Conference Publication
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Anisotropic Smoothing Regularization (AnSR) in Thirion's Demons Registration Evaluates Brain MRI Tissue Changes Post-Laser Ablation
Hwuang, E., Danish, S., Rusu, M., Sparks, R., Toth, R., Madabhushi, A. “Anisotropic Smoothing Regularization (AnSR) in Thirion's Demons Registration Evaluates Brain MRI Tissue Changes Post-Laser Ablation.” Conf Proc IEEE Eng Med Biol Soc. 2013.
Conference Publication
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Medial Axis Based Statistical Shape Model (MASSM): Applications to Prostate Segmentation
Toth, R., Sparks, R., Madabhushi, A., “Medial Axis Based Statistical Shape Model (MASSM): Applications to Prostate Segmentation,” ISBI 2011. doi: 10.1109/ISBI.2011.5872676
Conference Publication
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A Multi-Attribute, Non-Initializing, Texture Reconstruction Based Active Shape Model (MANTRA)
Toth, R., Chappellow, J., Rosen, M., Pungavkar, S., Kalyanpur, A., Madabhushi, A., “A Multi-Attribute, Non-Initializing, Texture Reconstruction Based Active Shape Model (MANTRA),” MICCAI 5241, pp. 653-661, 2008. doi: 10.1007/978-3-540-85988-8_78
Conference Publication
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Cadonc: An Integrated Toolkit for Evaluating Radiation Therapy Related Changes in the Prostate Using Multiparametric MRI
Viswanath, S., Tiwari, P., Chappelow, J., Toth, R., Kurhanewicz, J., Madabhushi, A., “Cadonc: An Integrated Toolkit for Evaluating Radiation Therapy Related Changes in the Prostate Using Multiparametric MRI,” ISBI 2011. doi: 10.1109/ISBI.2011.5872825
Conference Publication
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A Comprehensive Segmentation Registration and Cancer Detection Scheme on 3T in vivo Prostate DCE MRI
Viswanath, S, Chappelow, J, Toth, R, Linkinski, R, Bloch, B, Madabhushi, A., “A Comprehensive Segmentation Registration and Cancer Detection Scheme on 3T in vivo Prostate DCE MRI”, MICCAI, pp. 662-669, 2008. doi: 10.1007/978-3-540-85988-8_79
Conference Publication
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An Integrated Framework for Analyzing Three-Dimensional Shape Differences: Evaluating Prostate Morphometry
Sparks, R., Toth, R, Chappelow, J, Xiao, G, & Madabhushi, A. “An Integrated Framework for Analyzing Three-Dimensional Shape Differences: Evaluating Prostate Morphometry.” ISBI pp. 1081-1084, 2010. doi: 10.1109/ISBI.2010.5490180
Conference Publication
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Registration of Pre and Post Intensity Modulated Radiation Therapy Prostate MRI for Quantification of MR Imaging Marker Changes and Precise Local Prostate Deformations
Toth, R., Kurhanewicz, J., Madabhushi, A. “Registration of Pre and Post Intensity Modulated Radiation Therapy Prostate MRI for Quantification of MR Imaging Marker Changes and Precise Local Prostate Deformations” ISMRM 2013.
Conference Publication
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Quantitative evaluation of treatment related changes on multi-parametric MRI after laser interstitial thermal therapy of prostate cancer
Viswanath, S, Toth, R., Rusu, M., Sperling, D., Lepor, H., Futterer, J, Madabhushi, A., “Quantitative evaluation of treatment related changes on multi-parametric MRI after laser interstitial thermal therapy of prostate cancer”, SPIE Medical Imaging, 2013, vol 8671, 86711F. doi: 10.1117/12.2008037
Conference Publication
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A statistical deformation model (SDM) based regularizer for non-rigid image registration: application to registration of multimodal prostate MRI and histology
Prabu, S., Toth, R., Madabhushi, A., “A statistical deformation model (SDM) based regularizer for non-rigid image registration: application to registration of multimodal prostate MRI and histology,” SPIE Medical Imaging, 2013, vol 8676, 86760C. doi: 10.1117/12.2008707
Conference Publication
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Incorporating the Whole-Mount Prostate Histology Reconstruction Program Histostitcher© into the Extensible Imaging Platform (XIP) Framework
Toth, R., Chappelow, J., Kutter, O., Vetter, C., Russ, C., Feldman, M., Tomaszewski, J., Shih, N., Madabhushi, A., “Incorporating the Whole-Mount Prostate Histology Reconstruction Program Histostitcher© into the Extensible Imaging Platform (XIP) Framework,” SPIE Medical Imaging 8315, 2012. doi: 10.1117/12.912938

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